We processed and compiled all results from scientic reseach on CBD and Cannabis from the past 40 years. In this study from 1992 entitled Dronabinol stimulates appetite and causes weight gain in HIV patients, the authors Plasse T, Conant M, Gorter R, Shepard KV came to the following conclusions:
increase in appetite, trend toward weight gain.
To test the effect of dronabinol (delta-9- tetrahydrocannabinol) on appetite and weight in symptomatic HIV patients (pts). METHODS: Forty pts with symptomatic HIV infection who were actively losing weight were entered into this dose ranging study of dronabinol (Marinol, Roxane Laboratories, Columbus OH). After a one week baseline period, pts were treated for 4 weeks; to be evaluable for efficacy, patients had to receive at least 3 weeks' medication. Pts were weighed and completed a questionnaire on physical and psychological symptoms weekly; they completed 100mm visual analog scales for hunger before each meal. Of 40 pts entered, 10 withdrew due to suspected adverse effects of study medication and 7 due to other causes.
TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSIONS: In this open pilot study, dronabinol 2.5 mg bid was well tolerated and caused a significant increase in appetite, improvement of symptoms and a strong trend toward weight gain.
Plasse T, Conant M, Gorter R, Shepard KV
International Conference on AIDS 1992;8(3):122 (abstract no PuB 7442)
Type of publication
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